Marked decrease in Loa loa microfilaraemia six and twelve months after a single dose of ivermectin.
نویسندگان
چکیده
following ivermectin treatment. Tmnsaczions of the Royal Sociey of Tropical Medicine and Hygiene, 86, 287-288. Kombila, M., Duong, T. H. & Richard-knoble, D. (1995). Safety of ivermectin for treating onchocerciasis in populadons where loiasis is Co-endemic (Central Africa: Gabon), American Journal of Tmpical Medicine and Hygiene, 53, supplement, 260-261. Mak, J. W., Navaratnam, V., Grewel, J. S., Mansor, S. M. & Ambu, S. (1993). Treatment of subperiodic Brugia nialayi infection with a single dose of ivermectin. AniericanJournal of Tropical Medicine and Hygiene, 48,591-596. Martin-Prével, Y., Cosnefroy, J. Y., Ngari, P. & Pinder, M. (1993a). Reduction of microfilaraemia with single high-dose of ivermectin in loiasis. Lancez, 342,442. Martin-Prkel, Y., Cosnefroy, J. Y., Tshipamba, P., Ngari, P., Chodakewitz, J. A. & Finder, M. (1993b). Tolerance and efficacy of single high-dose ivermectin for the treatment of loiasis. American Journal of Tropical Medicine and Hygiene, 48, I nie, P. J. (1 992). Long-term suppression of microfilaraemia
منابع مشابه
Effect of Two or Six Doses 800 mg of Albendazole Every Two Months on Loa loa Microfilaraemia: A Double Blind, Randomized, Placebo-Controlled Trial.
BACKGROUND Loiasis is a parasitic infection endemic in the African rain forest caused by the filarial nematode Loa loa. Loiasis can be co-endemic with onchocerciasis and/or lymphatic filariasis. Ivermectin, the drug used in the control of these diseases, can induce serious adverse reactions in patients with high L loa microfilaraemia (LLM). A drug is needed which can lower LLM below the level t...
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We have studied the impact of large-scale treatment with ivermectin on the transmission of loiasis in a forest village in south Cameroon where loiasis was highly endemic, with a prevalence of 30%. After one year of parasitological and entomological surveillance without treatment, all consenting residents aged > 5 years received ivermectin 200 micrograms/kg every 3 months. For ethical reasons, t...
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In August 2002, 65 cases of Loa-associated neurological Serious Adverse Events were reported after ivermectin treatment. The first signs, occurring within the 12-24 hours following treatment, included fatigue, generalized arthralgia, and sometimes agitation, mutism, and incontinence. Disorders of consciousness, including coma, generally appeared between 24 and 72 hours, and showed a rapid varia...
متن کاملMapping the distribution of Loa loa in Cameroon in support of the African Programme for Onchocerciasis Control
BACKGROUND: Loa loa has recently emerged as a filarial worm of significant public health importance as a consequence of its impact on the African Programme for Onchocerciasis Control (APOC). Severe, sometimes fatal, encephalopathic reactions to ivermectin (the drug of choice for onchocerciasis control) have occurred in some individuals with high Loa loa microfilarial counts. Since high density ...
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BACKGROUND The risk of severe adverse events following treatment of onchocerciasis with ivermectin in areas co-endemic with loiasis currently compromises the development of control programmes and the treatment of co-infected individuals. We therefore assessed whether doxycycline treatment could be used without subsequent ivermectin administration to effectively deliver sustained effects on Onch...
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ورودعنوان ژورنال:
- Transactions of the Royal Society of Tropical Medicine and Hygiene
دوره 91 5 شماره
صفحات -
تاریخ انتشار 1997